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Cancer of the Vulva - Treatment 

Contents:

bulletTreatment Types
bulletTreatment by Stage
bulletFollow-up

Treatment Types

All stages of cancer of the vulva can be treated; all are not curable. Treatment of cancer of the vulva depends on the stage of the disease, the type of disease and the patient's age and overall medical condition. The three main types of treatment used are surgery (minor and major), radiation therapy and chemotherapy

Treatment by Stage 

An outline of the treatments generally administered at each stage is:
bulletStage 0

Treatment is by local excision for relatively small lesions up to a few centimetres in dimension. If the lesions are multifocal and/or widespread, then it may be better to treat these by a skinning vulvectomy. This involves literally skinning the abnormal area of the vulva and possibly covering the defect with a split skin graft. This will be done in a hospital under anaesthetic.

bulletStage I 

The primary approach is a wide local excision of the lesion. This may involve removal of one side of the vulva, called a hemivulvectomy. It is important to get at least 1 centimetre of normal tissue from around the cancer, to ensure that none remains. If the cancer comes close to the midline of the vulva, then it may be wise to treat the cancer by a whole excision of the vulva, called a radical vulvectomy.

If the cancer invades to a depth of more than 1 millimetre, then the lymph nodes should be removed from the groin. Whether this should be done for one or both groins depends on the size and site (location) of the cancer.
bulletStage II 

This would generally be treated by a radical vulvectomy, involving the removal of the whole vulva and removal of the lymph nodes in both groins. If cancer is found in the groin lymph nodes, then further treatment with radiation therapy to the pelvis may be advised.
bulletStage III 

This may be treated by radical vulvectomy involving the removal of the whole vulva and removal of the lymph nodes in both groins. However, the feasibility of this approach will depend very much on the degree to which the urethra, vagina or anus are affected. 

At times, and in order to minimise the surgery, initial treatment may be by radiation therapy and chemotherapy to reduce the size of the tumour, followed by surgical removal.
bulletStage IV 

In this group of patients, the treatment needs be individualised to suit the situation. It may involve a combination of surgery, radiation therapy and chemotherapy.
bulletRecurrent 

This will depend very much on the site (location) of the recurrence. It may involve surgical removal of the recurrence followed by radiotherapy, or radiation therapy by itself or with chemotherapy. These choices have to be made on an individual case-by-case basis.

Follow-up 

It is important that patients have proper follow-up after treatment for cancer of the vulva. Follow-up examination involves taking a brief history covering the time since the last visit. A physical examination is then undertaken with careful checking of the vulva and groins. The usual follow-up protocol is to be seen:
bulletevery 3 months for the first 2 years
bulletevery six months from 2 to 5 years
bulletyearly thereafter.

 

Prof Alex Crandon

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© 2003 Gynaecological Cancer Society .
Contact Mr John Gower Chief Executive,
Gynaecological Cancer Society, Room 2 Floor H,
Clinical Sciences Building. Royal Brisbane & Womens Hospital, Herston, Queensland, 4029
Phone: +61 7 3365 5216 Fax: +61 7 3635 5216
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