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Epithelial Ovarian Cancer- Treatment 

Contents:

bulletTreatment types
bulletFollow-up

Treatment types

All cases of ovarian cancer can be treated. Treatments will depend on the age of the patient, her desire to have children, the type of tumour and the stage of the tumour. There are three types of treatment used for ovarian cancer: surgery, radiation therapy and chemotherapy.

If the disease is limited to one ovary, and occurs in a young woman who wishes to retain her ability to bear children, then treatment would be removal of the fallopian tube and ovary on that side, as well as removal of the omentum and lymph nodes in the pelvis and para-aortic region on the same side as the tumour. A decision as to whether or not the patient also received chemotherapy would have to await the pathology report on this operation.

If the tumour was limited to the inside of the cyst on that ovary, and there was no evidence of anything on the surface of the tumour itself, the patient would not receive chemotherapy unless it was a clear cell tumour

If the disease has spread beyond one ovary (stage Ib or beyond) then generally the treatment will be to leave the patient with no visible evidence of tumour. This will usually require a hysterectomy, removal of both tubes and ovaries, removal of the omentum and multiple biopsies. If it is an advanced disease (i.e. Stage III) then bowel resections followed by chemotherapy may be required.

Surgery 

Surgery for ovarian cancer is a major operation. The patient will generally be in hospital for anywhere from 7-14 days depending on how fast she recovers from the surgery and whether or not she receives her first dose of chemotherapy while still in hospital.

Pain relief after surgery is usually very good. Most patients will have both an epidural and a general anaesthetic for their surgery. This means that they wake up quicker and recover more easily. The epidural can be left in for 3 days, during which time it will continue to provide pain relief. When it is removed, other medication may be given for pain relief, but by then the worst of the pain will have passed.

Follow-up 

It is important that patients have proper follow-up after care following treatment for ovarian cancer. These check-ups will generally involve a physical examination and a laboratory blood test called a CA 125 assay. Often the CA 125 level in a patient's blood is high before treatment and falls during surgery and chemotherapy. If the CA 125 level begins to rise again, it may be an indicator that the cancer has recurred. However, there may be other reasons, unrelated to cancer, for the CA 125 level to rise.

The usual follow-up protocol is to be seen:
bulletevery 3 months for the first 2 years
bulletevery six months from 2 to 5 years
bulletyearly thereafter.

 

Prof Alex Crandon

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© 2003 Gynaecological Cancer Society .
Contact Mr John Gower Chief Executive,
Gynaecological Cancer Society, Room 2 Floor H,
Clinical Sciences Building. Royal Brisbane & Womens Hospital, Herston, Queensland, 4029
Phone: +61 7 3365 5216 Fax: +61 7 3635 5216
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